김주영 교수

Introduction

김주영 (Joo Young Kim) 교수는 현재 연세대학교 의과대학 약리학교실 교수로 재직 중이며 KJY Lab.의 연구책임자입니다. KJY Lab.은 항체 기반 약물 개발에 집중하여, 항체 결합 후의 직접적인 세포 사멸 분자적 매커니즘 및 glycoengineer antiboby를 연구 개발하고 있습니다.

#상피세포학 #칼슘신호 #항체의약품

 

Education and Professional Experiences


  • 1998 학사: Department of Biology, Yonsei University
  • 2000 석사: Department of Biology Graduate School of Yonsei University
  • 2003 박사: Department of Pharmacology Graduate School of Yonsei University College of Medicine
  • 2003 – 2004 Research and teaching assistant, Department of Pharmacology, College of Medicine, Yonsei University
  • 2004 – 2006 Postdoctoral Fellow , Department of physiology, University of Texas Southwestern Medical Center at Dallas, USA
  • 2006 – 2007 Research Instructor , Department of Pharmacology, Yonsei University College of Medicine
  • 2007 – 2009 Full time Instructor , Department of Pharmacology, Yonsei University College of Medicine
  • 2009 – 2014 Assistant Professor , Department of Pharmacology, Yonsei University College of Medicine
  • 2015 – 2021 Associate Professor, Department of Pharmacology, Yonsei University College of Medicine
  • 2021 – 현재 Professor, Department of Pharmacology, Yonsei University College of Medicine

 

Major Publication


  • Kim, H.-Y., Park, M., Kang, C., Heo, W., Yoon, S.M., Lee, J., and Kim, J.Y. (2020). O-GlcNAcylation of light chain serine 12 mediates rituximab production doubled by thiamet G. Bioprocess and biosystems engineering, 10.1007/s00449-00020-02282-z.
  • Heo, W., Jin, N., Park, M.S., Kim, H.Y., Yoon, S.M., Lee, J., and Kim, J.Y. (2020). STIM1 knock-down decreases the affinity of obinutuzumab for CD20 by altering CD20 localization to Triton-soluble membrane. Clinical and experimental immunology, 10.1111/cei.13427.
  • Jin, N., Lee, J.W., Heo, W., Ryu, M.Y., So, M.K., Ko, B.J., Kim, H.Y., Yoon, S.M., Lee, J., Kim, J.Y., et al. (2019). Low binding affinity and reduced complement-dependent cell death efficacy of ofatumumab produced using a plant system (Nicotiana benthamiana L.). Protein expression and purification 159, 34-41.
  • H.M. Lim, W. Heo, J.W. Han, M.G. Lee, J.Y. Kim*, NPP1 is responsible for potent extracellular ATP hydrolysis as NTPDase1 in primary cultured murine microglia, Purinergic signalling, 14 (2018) 157-166.
  • J.W. Lee, W. Heo, J. Lee, N. Jin, S.M. Yoon, K.Y. Park, E.Y. Kim, W.T. Kim, J.Y. Kim*, The B cell death function of obinutuzumab-HDEL produced in plant (Nicotiana benthamiana L.) is equivalent to obinutuzumab produced in CHO cells, PLoS One, 13 (2018) e0191075.

 

Related link


Contact | jooyoungkim@yuhs.ac

작성 및 편집 | 서울시립대학교 김희형

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