정지헌 교수

주요경력

• 2002.03 ~ 2006.02 충남대학교 약학대학 제약학과 (약학사)
  2006.03 ~ 2013.02 서울대학교 약학대학 약제과학전공 (약학박사)
  2007.11 ~ 2008.01 University of Minnesota, School of Medicine (연수연구원)
  2008.08 ~ 2009.01 University of Minnesota, School of Medicine (연수연구원)
  2013.04 ~ 2013.08 서울대학교 종합약학연구소 (박사후연구원)
  2013.09 ~ 2019.08 영남대학교 약학대학 (조교수)
  2019.09 ~ 2022.02 영남대학교 약학대학 (부교수)
  2022.03 ~ 현재 성균관대학교 의과대학 (부교수)

주요관심연구

• 1. 표면개질 기술을 활용한 면역 억제형 췌도세포 개발
  2. 약물전달체 응용 줄기세포 의약품 생존율 향상 기술 개발
  3. 3차원 배양 기술을 활용한 세포 의약품 기능고도화 연구
  4. 약물전달체/세포 융합 헤테로스페로이드 개발
  5. 질환별 표적 약물전달시스템 개발

대표연구업적

• 1. Shobha Regmi*, Pawan Kumar Raut*, Shiva Pathak, Prakash Shrestha, Pil-Hoon Park**, Jee-Heon Jeong**, “Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction”, Autophagy (IF=16.02),17(10), Oct 2021, 2991-30102. Tiep Tien Nguyen, Cao Dai Phung, Jong Oh Kim, Chul Soon Yong, Jae-Ryong Kim, Simmyung Yook**, Jee-Heon Jeong**, “The impact of locally-delivered tacrolimus-releasing microspheres and polyethylene glycol-based islet surface modification on xenogeneic islet survival”, Journal of Controlled Release (IF=9.776), 336, Aug 2021, 274-284

  3. Shobha Regmi*, Yoogin Seo*, Ji-Su Ahn*, Shiva Pathak, Suman Acharya, Tiep Tien Nguyen, Simmyung Yook, Jong-Hyuk Sung, Jun-Beom Park, Jong Oh Kim, Chul Soon Young, Hyung-Sik Kim**, and Jee-Heon Jeong**, “Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration, Biomaterials (IF=12.479), 271, Apr 2021, 120752

  4. Tung Thanh Pham, Phuong Le Tran, Cao Dai Phung, Hanh Thuy Nguyen, Canh Hung Nguyen, Chul Soon Yong, Jong Oh Kim, Simmyung Yook**, Jee-Heon Jeong**, “Surface triggered in situ gelation for tunable conformal hydrogel coating of therapeutic cells and biomedical devices”, Advanced Functional Materials (IF=18.808), 31, May 2021, 2010169 (Back cover)

  5. Shiva Pathak*, Suman Acharya*, Shobha Regmi, Prakash Shrestha, Zhiwei You, Young Kyung Bae, Min Hui Park, Simmyung Yook, Jae-Ryong Kim, So Young Park, Daewon Jeong, Chul Soon Yong, Jong Oh Kim, Jae Hoon Chang**, Jee-Heon Jeong**, “Particulate-Based Single-Dose Local Immunosuppressive Regimen for Inducing Tolerogenic Dendritic Cells in Xenogeneic Islet Transplantation”, Advanced Healthcare Materials (IF=9.933), 10(2), Jan 2021, 2001157

  6. Tiep Tien Nguyen, Fakhrossadat Emami, Simmyung Yook**, Hanh Thuy Nguyen, Tung Thanh Pham, Shiva Pathak, Shobha Regmi, Jong Oh. Kim, Chul Soon Yong, Jae-Ryong Kim, Jee-Heon Jeong** “Local release of NECA (5’-(N-ehylcarboxamido)adenosine) from implantable polymeric sheets for enhanced islet revascularization in extrahepatic transplantation site”, Journal of Controlled Release (IF=9.776), 312, May 2020, 509-518

  7. Shobha Regmi, Shiva Pathak, Mahesh Raj Nepal, Prakash Shrestha, Junhyeung Pakr, Jong Oh Kim, Chul Soon Yong, Dong-Young Choi, Jae-Hoon Chang, Tae Cheon Jeong, Gorka Orive, Simmyung Yook**, Jee-Heon Jeong** “Inflammation-triggered local drug release ameliorates colitis by inhibiting dendritic cell migration and Th1/Th17 differentiation”, Journal of Controlled Release (IF=9.776), 316 Dec 2019, 138-149

  8. Tiep Tien Nguyen*, Tung Thanh Pham*, Hanh Thuy Nguyen, Mahesh Raj Nepal, Cao Dai Phung, Zhiwei You, Nikita Katila, Nirmala Tilija Pun, Dong-Young Choi, Pil-Hoon Park, Chul Soon Yong, Jong Oh Kim, Simmyung Yook**, Jee-Heon Jeong**, “Engineering cell-pharicle hybrids” of pancreatic islets and bioadhesive FK506-loaded polymeric microspheres for local immunomodulation in xenogeneic islet transplantation”, Biomaterials (IF=12.479), 221, Nov 2019, 119415

  9. Shiva Pathak*, Tung Thanh Pham*, Jee-Heon Jeong**, Youngro Byun**, “Immunoisolation of pancreatic islets via thin-layer surface modification”, Journal of Controlled Release (IF=9.776), 305(10), July 2019, 176-193

  10. Shiva Pathak, Shobha Regmi, Prakash Shrestha, Inho Choi, Kyoung-Oh Doh, Jee-Heon Jeong, “Mesenchymal stem cell capping on ECM-anchored caspase inhibitor-loaded PLGA microspheres for intraperitoneal injection in DSS-induced murine colitis”, Small (IF=13.281), 15(23), June 2019, 1901269 (Cover Story)

편집 | 허수빈 (아주대학교)